> ## Documentation Index
> Fetch the complete documentation index at: https://docs.rafflesia.ai/llms.txt
> Use this file to discover all available pages before exploring further.

# Homology search

> One endpoint over immutable, object-storage-backed releases — POST /v1/homology.

Rafflesia's homology engine compiles a biological corpus once into an immutable
release, then answers a protein-sequence query by range-reading only the bytes
that query needs. Every result comes back as a named measurement with full
provenance — never a bare score, and never a "homolog" verdict.

One call starts the work: **`POST /v1/homology`**. The computation is
durable, so you then retrieve it and page its results by id.

<Columns cols={2}>
  <Card title="Quickstart" icon="terminal" href="/homology-search/quickstart">
    Run a computation, wait or poll, page the results.
  </Card>

  <Card title="Architecture" icon="layers" href="/homology-search/architecture">
    Immutable releases, byte-range reads, and where the cost goes.
  </Card>
</Columns>

## Next steps

* Run your first computation in the [Quickstart](/homology-search/quickstart).
* See how immutable releases and byte-range reads work in [Architecture](/homology-search/architecture).
* Read the request and response fields in the
  [API reference](/api-reference/introduction).